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Global Signaling Profiling in a Human Model of Tumorigenic Progression Indicates a Role for Alternative RNA Splicing in Cellular Reprogramming

Intracellular signaling is controlled to a large extent by the phosphorylation status of proteins. To determine how human breast cells can be reprogrammed during tumorigenic progression, we profiled cell lines in the MCF10A lineage by phosphoproteomic analyses. A large cluster of proteins involved i...

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Detalles Bibliográficos
Autores principales:	Caruso, Joseph A., Carruthers, Nicholas J., Thibodeau, Bryan, Geddes, Timothy J., Dombkowski, Alan A., Stemmer, Paul M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213538/ https://www.ncbi.nlm.nih.gov/pubmed/30241319 http://dx.doi.org/10.3390/ijms19102847

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