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Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism

Reduced therapeutic efficacy of sorafenib, a first-generation multikinase inhibitor, is often observed during the treatment of advanced hepatocellular carcinoma (HCC). Emodin is an active component of Chinese herbs, and is effective against leukemia, lung cancer, colon cancer, pancreatic cancer, and...

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Detalles Bibliográficos
Autores principales: Kim, Young-Seon, Lee, Yoon-Mi, Oh, Taek-In, Shin, Dong Hoon, Kim, Geon-Hee, Kan, Sang-Yeon, Kang, Hyeji, Kim, Ji Hyung, Kim, Byeong Mo, Yim, Woo Jong, Lim, Ji-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213641/
https://www.ncbi.nlm.nih.gov/pubmed/30321984
http://dx.doi.org/10.3390/ijms19103127

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