Non-Human Primate Models of Enteric Viral Infections

There is an important role non-human primates (NHP) play in biomedical research. Phylogenetic proximity of any of the NHP species to Homo sapiens assures that much better translatability of research outcomes from model studies involving human diseases can be achieved than from those generated with o...

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Detalles Bibliográficos
Autor principal: Sestak, Karol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213648/
https://www.ncbi.nlm.nih.gov/pubmed/30301125
http://dx.doi.org/10.3390/v10100544
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author Sestak, Karol
author_facet Sestak, Karol
author_sort Sestak, Karol
collection PubMed
description There is an important role non-human primates (NHP) play in biomedical research. Phylogenetic proximity of any of the NHP species to Homo sapiens assures that much better translatability of research outcomes from model studies involving human diseases can be achieved than from those generated with other pre-clinical systems. Our group and others used during past two decades NHPs in research directed towards viral and autoimmune disorders of the gastrointestinal tract. This review summarizes progress made in the area of enteric viral infections including its applicability to human disease.
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spelling pubmed-62136482018-11-09 Non-Human Primate Models of Enteric Viral Infections Sestak, Karol Viruses Review There is an important role non-human primates (NHP) play in biomedical research. Phylogenetic proximity of any of the NHP species to Homo sapiens assures that much better translatability of research outcomes from model studies involving human diseases can be achieved than from those generated with other pre-clinical systems. Our group and others used during past two decades NHPs in research directed towards viral and autoimmune disorders of the gastrointestinal tract. This review summarizes progress made in the area of enteric viral infections including its applicability to human disease. MDPI 2018-10-05 /pmc/articles/PMC6213648/ /pubmed/30301125 http://dx.doi.org/10.3390/v10100544 Text en © 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sestak, Karol
Non-Human Primate Models of Enteric Viral Infections
title Non-Human Primate Models of Enteric Viral Infections
title_full Non-Human Primate Models of Enteric Viral Infections
title_fullStr Non-Human Primate Models of Enteric Viral Infections
title_full_unstemmed Non-Human Primate Models of Enteric Viral Infections
title_short Non-Human Primate Models of Enteric Viral Infections
title_sort non-human primate models of enteric viral infections
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213648/
https://www.ncbi.nlm.nih.gov/pubmed/30301125
http://dx.doi.org/10.3390/v10100544
work_keys_str_mv AT sestakkarol nonhumanprimatemodelsofentericviralinfections

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