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Current Disease-Targets for Oleocanthal as Promising Natural Therapeutic Agent

The broad number of health benefits which can be obtained from the long-term consumption of olive oil are attributed mainly to its phenolic fraction. Many olive oil phenolics have been studied deeply since their discovery due to their bioactivity properties, such as Hydroxytyrosol. Similarly, in the...

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Detalles Bibliográficos
Autores principales: Segura-Carretero, Antonio, Curiel, Jose Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213726/
https://www.ncbi.nlm.nih.gov/pubmed/30250008
http://dx.doi.org/10.3390/ijms19102899
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author Segura-Carretero, Antonio
Curiel, Jose Antonio
author_facet Segura-Carretero, Antonio
Curiel, Jose Antonio
author_sort Segura-Carretero, Antonio
collection PubMed
description The broad number of health benefits which can be obtained from the long-term consumption of olive oil are attributed mainly to its phenolic fraction. Many olive oil phenolics have been studied deeply since their discovery due to their bioactivity properties, such as Hydroxytyrosol. Similarly, in the last decade, the special attention of researchers has been addressed to Oleocanthal (OC). This olive oil phenolic compound has recently emerged as a potential therapeutic agent against a variety of diseases, including cancer, inflammation, and neurodegenerative and cardiovascular diseases. Recently, different underlying mechanisms of OC against these diseases have been explored. This review summarizes the current literature on OC to date, and focuses on its promising bioactivities against different disease-targets.
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spelling pubmed-62137262018-11-14 Current Disease-Targets for Oleocanthal as Promising Natural Therapeutic Agent Segura-Carretero, Antonio Curiel, Jose Antonio Int J Mol Sci Review The broad number of health benefits which can be obtained from the long-term consumption of olive oil are attributed mainly to its phenolic fraction. Many olive oil phenolics have been studied deeply since their discovery due to their bioactivity properties, such as Hydroxytyrosol. Similarly, in the last decade, the special attention of researchers has been addressed to Oleocanthal (OC). This olive oil phenolic compound has recently emerged as a potential therapeutic agent against a variety of diseases, including cancer, inflammation, and neurodegenerative and cardiovascular diseases. Recently, different underlying mechanisms of OC against these diseases have been explored. This review summarizes the current literature on OC to date, and focuses on its promising bioactivities against different disease-targets. MDPI 2018-09-24 /pmc/articles/PMC6213726/ /pubmed/30250008 http://dx.doi.org/10.3390/ijms19102899 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Segura-Carretero, Antonio
Curiel, Jose Antonio
Current Disease-Targets for Oleocanthal as Promising Natural Therapeutic Agent
title Current Disease-Targets for Oleocanthal as Promising Natural Therapeutic Agent
title_full Current Disease-Targets for Oleocanthal as Promising Natural Therapeutic Agent
title_fullStr Current Disease-Targets for Oleocanthal as Promising Natural Therapeutic Agent
title_full_unstemmed Current Disease-Targets for Oleocanthal as Promising Natural Therapeutic Agent
title_short Current Disease-Targets for Oleocanthal as Promising Natural Therapeutic Agent
title_sort current disease-targets for oleocanthal as promising natural therapeutic agent
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213726/
https://www.ncbi.nlm.nih.gov/pubmed/30250008
http://dx.doi.org/10.3390/ijms19102899
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