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Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine

Live attenuated influenza vaccines (LAIV) have prevented morbidity and mortality associated with influenza viral infections for many years and represent the best therapeutic option to protect against influenza viral infections in humans. However, the development of LAIV has traditionally relied on e...

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Detalles Bibliográficos
Autores principales: Martínez-Sobrido, Luis, Peersen, Olve, Nogales, Aitor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213772/
https://www.ncbi.nlm.nih.gov/pubmed/30326610
http://dx.doi.org/10.3390/v10100560