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Hormesis: Path and Progression to Significance
This paper tells the story of how hormesis became recognized as a fundamental concept in biology, affecting toxicology, microbiology, medicine, public health, agriculture, and all areas related to enhancing biological performance. This paper assesses how hormesis enhances resilience to normal aging...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213774/ https://www.ncbi.nlm.nih.gov/pubmed/30248927 http://dx.doi.org/10.3390/ijms19102871 |
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author | Calabrese, Edward J. |
author_facet | Calabrese, Edward J. |
author_sort | Calabrese, Edward J. |
collection | PubMed |
description | This paper tells the story of how hormesis became recognized as a fundamental concept in biology, affecting toxicology, microbiology, medicine, public health, agriculture, and all areas related to enhancing biological performance. This paper assesses how hormesis enhances resilience to normal aging and protects against a broad spectrum of neurodegenerative, cardiovascular, and other diseases, as well as trauma and other threats to health and well-being. This paper also explains the application of hormesis to several neurodegenerative diseases such as Parkinson’s and Huntington’s disease, macrophage polarization and its systematic adaptive protections, and the role of hormesis in enhancing stem cell functioning and medical applications. |
format | Online Article Text |
id | pubmed-6213774 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62137742018-11-14 Hormesis: Path and Progression to Significance Calabrese, Edward J. Int J Mol Sci Review This paper tells the story of how hormesis became recognized as a fundamental concept in biology, affecting toxicology, microbiology, medicine, public health, agriculture, and all areas related to enhancing biological performance. This paper assesses how hormesis enhances resilience to normal aging and protects against a broad spectrum of neurodegenerative, cardiovascular, and other diseases, as well as trauma and other threats to health and well-being. This paper also explains the application of hormesis to several neurodegenerative diseases such as Parkinson’s and Huntington’s disease, macrophage polarization and its systematic adaptive protections, and the role of hormesis in enhancing stem cell functioning and medical applications. MDPI 2018-09-21 /pmc/articles/PMC6213774/ /pubmed/30248927 http://dx.doi.org/10.3390/ijms19102871 Text en © 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Calabrese, Edward J. Hormesis: Path and Progression to Significance |
title | Hormesis: Path and Progression to Significance |
title_full | Hormesis: Path and Progression to Significance |
title_fullStr | Hormesis: Path and Progression to Significance |
title_full_unstemmed | Hormesis: Path and Progression to Significance |
title_short | Hormesis: Path and Progression to Significance |
title_sort | hormesis: path and progression to significance |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213774/ https://www.ncbi.nlm.nih.gov/pubmed/30248927 http://dx.doi.org/10.3390/ijms19102871 |
work_keys_str_mv | AT calabreseedwardj hormesispathandprogressiontosignificance |