Cargando…

Metabolic Effects of Metformin in the Failing Heart

Accumulating evidence shows that metformin is an insulin-sensitizing antidiabetic drug widely used in the treatment of type 2 diabetes mellitus (T2DM), which can exert favorable effects on cardiovascular risk and may be safely used in patients with heart failure (HF), and even able to reduce the inc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dziubak, Aleksandra, Wójcicka, Grażyna, Wojtak, Andrzej, Bełtowski, Jerzy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213955/ https://www.ncbi.nlm.nih.gov/pubmed/30248910 http://dx.doi.org/10.3390/ijms19102869

Ejemplares similares

Paraoxonase 1 Phenotype and Protein N-Homocysteinylation in Patients with Rheumatoid Arthritis: Implications for Cardiovascular Disease
por: Parada-Turska, Jolanta, et al.
Publicado: (2020)

Cladribine Treatment Improved Homocysteine Metabolism and Increased Total Serum Antioxidant Activity in Secondary Progressive Multiple Sclerosis Patients
por: Jamroz-Wiśniewska, Anna, et al.
Publicado: (2020)

Role of Hydrogen Sulfide and Polysulfides in the Regulation of Lipolysis in the Adipose Tissue: Possible Implications for the Pathogenesis of Metabolic Syndrome
por: Bełtowski, Jerzy, et al.
Publicado: (2022)

Targeting Mitochondrial Metabolism to Save the Failing Heart
por: Schenkl, Christina, et al.
Publicado: (2023)

Tempol, a Membrane-Permeable Radical Scavenger, Exhibits Anti-Inflammatory and Cardioprotective Effects in the Cerulein-Induced Pancreatitis Rat Model
por: Marciniak, Andrzej, et al.
Publicado: (2016)

Hydrogen Sulfide in the Adipose Tissue—Physiology, Pathology and a Target for Pharmacotherapy
por: Bełtowski, Jerzy, et al.
Publicado: (2016)

Hydrogen Sulfide and Endothelium-Dependent Vasorelaxation
por: Bełtowski, Jerzy, et al.
Publicado: (2014)

Oncometabolism: A Paradigm for the Metabolic Remodeling of the Failing Heart
por: Kuhn, Annika-Ricarda, et al.
Publicado: (2022)

ENERGY METABOLISM OF THE FAILING HEART
por: Decherd, George, et al.
Publicado: (1934)

Leptin and the Regulation of Renal Sodium Handling and Renal Na(+)-Transporting ATPases: Role in the Pathogenesis of Arterial Hypertension
por: Bełtowski, Jerzy
Publicado: (2010)

Microalbuminúria e o Risco de Mortalidade em Pacientes com Insuficiência Cardíaca Aguda
por: Beltowski, Jerzy
Publicado: (2022)

Rethinking cardiac metabolism: metabolic cycles to refuel and rebuild the failing heart
por: Taegtmeyer, Heinrich, et al.
Publicado: (2014)

Thiazolidinedione-Induced Fluid Retention: Recent Insights into the Molecular Mechanisms
por: Bełtowski, Jerzy, et al.
Publicado: (2013)

Loss of Metabolic Flexibility in the Failing Heart
por: Karwi, Qutuba G., et al.
Publicado: (2018)

Arrhythmogenic Remodeling in the Failing Heart
por: Husti, Zoltán, et al.
Publicado: (2021)

Retained Metabolic Flexibility of the Failing Human Heart
por: Watson, William D., et al.
Publicado: (2023)

Altered Mitochondrial Metabolism and Mechanosensation in the Failing Heart: Focus on Intracellular Calcium Signaling
por: Cabassi, Aderville, et al.
Publicado: (2017)

Effect of Exogenous Hydrogen Sulfide and Polysulfide Donors on Insulin Sensitivity of the Adipose Tissue
por: Kowalczyk-Bołtuć, Jolanta, et al.
Publicado: (2022)

Metabolic Action of Metformin
por: Szymczak-Pajor, Izabela, et al.
Publicado: (2022)

Mitochondrial Bioenergetics and Dynamism in the Failing Heart
por: Morciano, Giampaolo, et al.
Publicado: (2021)

Left Ventricular Assist Device Effects on Metabolic Substrates in the Failing Heart
por: Weitzel, Lindsay B., et al.
Publicado: (2013)

The Failing Heart
por: Wells, S. Russell
Publicado: (1907)

An Overview of the Biological Activity of Pyrrolo[3,4-c]pyridine Derivatives
por: Wójcicka, Anna, et al.
Publicado: (2021)

Cardiac damage in athlete’s heart: When the “supernormal” heart fails!
por: Carbone, Andreina, et al.
Publicado: (2017)

Mechanisms of Contraction of the Normal and Failing Heart
por: Goodyer, A. V. N.
Publicado: (1969)

Metformin in heart failure patients
por: Kinsara, Abdulhalim Jamal, et al.
Publicado: (2018)

Neuromodulation of the Failing Heart: Lost in Translation?
por: Byku, Mirnela, et al.
Publicado: (2016)

Fibroblasts in the Infarcted, Remodeling, and Failing Heart
por: Humeres, Claudio, et al.
Publicado: (2019)

Abnormalities of calcium metabolism and myocardial contractility depression in the failing heart
por: Lehnart, Stephan E., et al.
Publicado: (2009)

Mending the failing heart
por: Wang, Xiaowei, et al.
Publicado: (2019)

Diastolic myofilament dysfunction in the failing human heart
por: van der Velden, Jolanda
Publicado: (2011)

Failing Heart Transplants and Rejection—A Cellular Perspective
por: Hurskainen, Maria, et al.
Publicado: (2021)

Myocardial oedema: pathophysiological basis and implications for the failing heart
por: Vasques‐Nóvoa, Francisco, et al.
Publicado: (2022)

Effects of Metformin in Heart Failure: From Pathophysiological Rationale to Clinical Evidence
por: Salvatore, Teresa, et al.
Publicado: (2021)

Re-balancing cellular energy substrate metabolism to mend the failing heart(☆)
por: Glatz, Jan F.C., et al.
Publicado: (2019)

Experimental Study of Filtration Materials Used in the Car Air Intake
por: Dziubak, Tadeusz, et al.
Publicado: (2020)

Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metformin
por: Sivalingam, Vanitha N., et al.
Publicado: (2019)

Signaling cascades in the failing heart and emerging therapeutic strategies
por: He, Xin, et al.
Publicado: (2022)

Iron Overload, Oxidative Stress, and Ferroptosis in the Failing Heart and Liver
por: Mancardi, Daniele, et al.
Publicado: (2021)

Clinical and Molecular Aspects of Iron Metabolism in Failing Myocytes
por: Kozłowska, Bogna, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ct5s3toco6rd0sr97p59snqs0n