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sEst: Accurate Sex-Estimation and Abnormality Detection in Methylation Microarray Data

DNA methylation influences predisposition, development and prognosis for many diseases, including cancer. However, it is not uncommon to encounter samples with incorrect sex labelling or atypical sex chromosome arrangement. Sex is one of the strongest influencers of the genomic distribution of DNA m...

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Detalles Bibliográficos
Autores principales: Jung, Chol-Hee, Park, Daniel J., Georgeson, Peter, Mahmood, Khalid, Milne, Roger L., Southey, Melissa C., Pope, Bernard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213967/
https://www.ncbi.nlm.nih.gov/pubmed/30326623
http://dx.doi.org/10.3390/ijms19103172

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