Cargando…

HPV-18 E6 Oncoprotein and Its Spliced Isoform E6*I Regulate the Wnt/β-Catenin Cell Signaling Pathway through the TCF-4 Transcriptional Factor

The Wnt/β-catenin signaling pathway regulates cell proliferation and differentiation and its aberrant activation in cervical cancer has been described. Persistent infection with high risk human papillomavirus (HR-HPV) is the most important factor for the development of this neoplasia, since E6 and E...

Descripción completa

Detalles Bibliográficos
Autores principales:	Muñoz-Bello, J. Omar, Olmedo-Nieva, Leslie, Castro-Muñoz, Leonardo Josué, Manzo-Merino, Joaquín, Contreras-Paredes, Adriana, González-Espinosa, Claudia, López-Saavedra, Alejandro, Lizano, Marcela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214013/ https://www.ncbi.nlm.nih.gov/pubmed/30322153 http://dx.doi.org/10.3390/ijms19103153

Ejemplares similares

Regulation of the Wnt/β-Catenin Signaling Pathway by Human Papillomavirus E6 and E7 Oncoproteins
por: Muñoz Bello, Jesus Omar, et al.
Publicado: (2015)

The Role of E6 Spliced Isoforms (E6*) in Human Papillomavirus-Induced Carcinogenesis
por: Olmedo-Nieva, Leslie, et al.
Publicado: (2018)

HPV16 E6 and E7 Oncoproteins Stimulate the Glutamine Pathway Maintaining Cell Proliferation in a SNAT1-Dependent Fashion
por: Ortiz-Pedraza, Yunuen, et al.
Publicado: (2023)

RIPOR2 Expression Decreased by HPV-16 E6 and E7 Oncoproteins: An Opportunity in the Search for Prognostic Biomarkers in Cervical Cancer
por: Olmedo-Nieva, Leslie, et al.
Publicado: (2022)

The Human Papillomavirus (HPV) E1 protein regulates the expression of cellular genes involved in immune response
por: Castro-Muñoz, Leonardo Josué, et al.
Publicado: (2019)

The Human Papillomavirus (HPV) E6 Oncoprotein Regulates CD40 Expression via the AT-Hook Transcription Factor AKNA
por: Manzo-Merino, Joaquin, et al.
Publicado: (2018)

Ubiquitination of the HPV Oncoprotein E6 Is Critical for E6/E6AP-Mediated p53 Degradation
por: Li, Siying, et al.
Publicado: (2019)

Interaction of the Human Papillomavirus E6 Oncoprotein with Sorting Nexin 27 Modulates Endocytic Cargo Transport Pathways
por: Ganti, Ketaki, et al.
Publicado: (2016)

Expression of the HPV18/E6 oncoprotein induces DNA damage
por: Gutierrez, Elva I. Cortes, et al.
Publicado: (2017)

Mechanisms of Vasculogenic Mimicry in Ovarian Cancer
por: Ayala-Domínguez, Lízbeth, et al.
Publicado: (2019)

The Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 Oncoproteins in the Orchestration of Carcinogenesis
por: Basukala, Om, et al.
Publicado: (2021)

Functional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical Sites
por: Tomaić, Vjekoslav
Publicado: (2016)

The HPV E6 oncoprotein targets histone methyltransferases for modulating specific gene transcription
por: Hsu, C-H, et al.
Publicado: (2012)

An RNA Aptamer Targets the PDZ-Binding Motif of the HPV16 E6 Oncoprotein
por: Belyaeva, Tamara A., et al.
Publicado: (2014)

Docosahexaenoic acid induces the degradation of HPV E6/E7 oncoproteins by activating the ubiquitin–proteasome system
por: Jing, K, et al.
Publicado: (2014)

Role of the JAK/STAT Pathway in Cervical Cancer: Its Relationship with HPV E6/E7 Oncoproteins
por: Gutiérrez-Hoya, Adriana, et al.
Publicado: (2020)

HPV16-E6 Oncoprotein Activates TGF-β and Wnt/β-Catenin Pathways in the Epithelium-Mesenchymal Transition of Cataracts in a Transgenic Mouse Model
por: Rodríguez-Uribe, Genaro, et al.
Publicado: (2018)

IRF-1 Inhibits Angiogenic Activity of HPV16 E6 Oncoprotein in Cervical Cancer
por: Rho, Seung Bae, et al.
Publicado: (2020)

Detection of HPV E6 oncoprotein from urine via a novel immunochromatographic assay
por: de Oliveira, Cristina Mendes, et al.
Publicado: (2020)

Molecular Landscape and Computational Screening of the Natural inhibitors against HPV16 E6 Oncoprotein
por: Juneja, Tanzil, et al.
Publicado: (2021)

Intrabodies targeting human papillomavirus 16 E6 and E7 oncoproteins for therapy of established HPV-associated tumors
por: Paolini, Francesca, et al.
Publicado: (2021)

The E6AP Binding Pocket of the HPV16 E6 Oncoprotein Provides a Docking Site for a Small Inhibitory Peptide Unrelated to E6AP, Indicating Druggability of E6
por: Zanier, Katia, et al.
Publicado: (2014)

Role of HPV18 E6 in PKB signal transduction pathways
por: Contreras, Adriana, et al.
Publicado: (2007)

Elucidating Molecular Interactions of Natural Inhibitors with HPV-16 E6 Oncoprotein through Docking Analysis
por: Kumar, Satish, et al.
Publicado: (2014)

HPV E6 and E7 oncoproteins cooperatively alter the expression of Disc Large 1 polarity protein in epithelial cells
por: Dizanzo, María Paula, et al.
Publicado: (2020)

E6^E7, a Novel Splice Isoform Protein of Human Papillomavirus 16, Stabilizes Viral E6 and E7 Oncoproteins via HSP90 and GRP78
por: Ajiro, Masahiko, et al.
Publicado: (2015)

The high‐risk HPV E6 proteins modify the activity of the eIF4E protein via the MEK/ERK and AKT/PKB pathways
por: Morales‐Garcia, Vicente, et al.
Publicado: (2020)

HPV Prevalence and Predictive Biomarkers for Oropharyngeal Squamous Cell Carcinoma in Mexican Patients
por: Reyes-Hernández, Diego Octavio, et al.
Publicado: (2022)

Targeting the Two Oncogenic Functional Sites of the HPV E6 Oncoprotein with a High-Affinity Bivalent Ligand**
por: Ramirez, Juan, et al.
Publicado: (2015)

Resveratrol and Pterostilbene Exhibit Anticancer Properties Involving the Downregulation of HPV Oncoprotein E6 in Cervical Cancer Cells
por: Chatterjee, Kaushiki, et al.
Publicado: (2018)

The PDZ-Binding Motif of HPV16-E6 Oncoprotein Modulates the Keratinization and Stemness Transcriptional Profile In Vivo
por: Cortés-Malagón, Enoc Mariano, et al.
Publicado: (2017)

Novel Affibody Molecules Targeting the HPV16 E6 Oncoprotein Inhibited the Proliferation of Cervical Cancer Cells
por: Zhu, Jinshun, et al.
Publicado: (2021)

Comparative Analysis of Alpha and Beta HPV E6 Oncoproteins: Insights into Functional Distinctions and Divergent Mechanisms of Pathogenesis
por: Skelin, Josipa, et al.
Publicado: (2023)

Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins
por: Buonomo, Tonia, et al.
Publicado: (2011)

Development and validation of a multiplex immunoassay for the simultaneous quantification of type-specific IgG antibodies to E6/E7 oncoproteins of HPV16 and HPV18
por: Layman, Hans, et al.
Publicado: (2020)

Uneven distribution of HPV 16 E6 prototype and variant (L83V) oncoprotein in cervical neoplastic lesions
por: Andersson, S, et al.
Publicado: (2000)

In silico prediction of structural changes in human papillomavirus type 16 (HPV16) E6 oncoprotein and its variants
por: Rodríguez-Ruiz, Hugo Alberto, et al.
Publicado: (2019)

Production of functional, stable, unmutated recombinant human papillomavirus E6 oncoprotein: implications for HPV-tumor diagnosis and therapy
por: Illiano, Elena, et al.
Publicado: (2016)

Inhibition of kinase IKKβ suppresses cellular abnormalities induced by the human papillomavirus oncoprotein HPV 18E6
por: Padash Barmchi, Mojgan, et al.
Publicado: (2021)

HPV E6, E6AP and cervical cancer
por: Beaudenon, Sylvie, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_noq665bphdj9o0eeqfqrn4fjrj