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Anti-Angiogenic miR-222, miR-195, and miR-21a Plasma Levels in T1DM Are Improved by Metformin Therapy, Thus Elucidating Its Cardioprotective Effect: The MERIT Study

Type 1 diabetes (T1DM) is associated with increased cardiovascular disease (CVD) and reduced life expectancy. We thus hypothesized that anti-angiogenic miRs are increased in T1DM, and the cardioprotective effect of metformin is mediated via reducing those miRs. In an open label, case-controlled stud...

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Detalles Bibliográficos
Autores principales:	Ahmed, Fahad W., Bakhashab, Sherin, Bastaman, Inda T., Crossland, Rachel E., Glanville, Michael, Weaver, Jolanta U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214022/ https://www.ncbi.nlm.nih.gov/pubmed/30347712 http://dx.doi.org/10.3390/ijms19103242

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