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Type I Interferon Signaling Is Required for Dacryoadenitis in the Nonobese Diabetic Mouse Model of Sjögren Syndrome

Nonobese diabetic (NOD) mice spontaneously develop lacrimal and salivary gland autoimmunity similar to human Sjögren syndrome. In both humans and NOD mice, the early immune response that drives T-cell infiltration into lacrimal and salivary glands is poorly understood. In NOD mice, lacrimal gland au...

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Detalles Bibliográficos
Autores principales: Chaly, Yury, Barr, Jennifer Y., Sullivan, David A., Thomas, Helen E., Brodnicki, Thomas C., Lieberman, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214106/
https://www.ncbi.nlm.nih.gov/pubmed/30347820
http://dx.doi.org/10.3390/ijms19103259

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