Rhabdomyolysis with Peripheral Neuropathy: A Case Series and Literature Review

Case series Patients: Female, 59 • Male, 52 • Female, 29 Final Diagnosis: Rhabdomyolysis Symptoms: Limited movement ability Medication: — Clinical Procedure: — Specialty: Neurology OBJECTIVE: Unusual clinical course BACKGROUND: Rhabdomyolysis is a syndrome characterized by muscle necrosis and secretion of intracellular muscle components into the blood circulation. Acute compartment syndrome is a potential complication of severe rhabdomyolysis. CASE REPORTS: We report 3 cases of compartment syndrome-related peripheral neuropathy in alcoholic individuals with rhabdomyolysis. All patients were confirmed to have peripheral neuropathy by electrophysiologic studies. CONCLUSIONS: Patients with underlying metabolic abnormalities, such as those related to long-term alcoholism, should be aware that rhabdomyolysis is likely to cause neurological abnormalities.