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Blocking PD1/PDL1 Interactions Together with MLN4924 Therapy is a Potential Strategy for Glioma Treatment

OBJECTIVE: MLN4924, a pharmacological inhibitor of cullin neddylation, resulted in glioma cell apoptosis, deregulation of the S-phase of DNA synthesis and thus, offers great potential for the treatment of brain tumours. However, targeting the neddylation pathway with an MLN4924 treatment stabilized...

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Detalles Bibliográficos
Autores principales:	Filippova, Natalia, Yang, Xiuhua, An, Zixiao, Nabors, Louis B, Pereboeva, Larisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214201/ https://www.ncbi.nlm.nih.gov/pubmed/30393513 http://dx.doi.org/10.4172/1948-5956.1000543

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