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A mutant cell library for systematic analysis of heparan sulfate structure-function relationships

Heparan sulfate (HS) is a complex linear polysaccharide that modulates a wide range of biological functions. Elucidating the structure-function relationship of HS has been challenging. Here we report the generation of a HS mutant mouse lung endothelial cell library by systematic deletion of HS genes...

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Detalles Bibliográficos
Autores principales:	Qiu, Hong, Shi, Songshan, Yue, Jingwen, Xin, Meng, Nairn, Alison V, Lin, Lei, Liu, Xinyue, Li, Guoyun, Archer-Hartmann, Stephanie A, Dela Rosa, Mitche, Galizzi, Melina, Wang, Shunchun, Zhang, Fuming, Azadi, Parastoo, van Kuppevelt, Toin H., Cardoso, Wellington V., Kimata, Koji, Ai, Xingbin, Moremen, Kelley W, Esko, Jeffrey D., Linhardt, Robert J., Wang, Lianchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214364/ https://www.ncbi.nlm.nih.gov/pubmed/30377379 http://dx.doi.org/10.1038/s41592-018-0189-6

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