Dexmedetomidine protects the developing rat brain against the neurotoxicity wrought by sevoflurane: role of autophagy and Drp1–Bax signaling

BACKGROUND: The effect of sevoflurane on the nervous system is controversial. As an adjuvant anesthetic, dexmedetomidine has a protective role in various nerve-injury diseases. We investigated the effect of dexmedetomidine on injury to the developing brain induced by sevoflurane anesthesia, and if a...

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Detalles Bibliográficos
Autores principales: Shan, Yangyang, Sun, Shiwei, Yang, Fan, Shang, Nan, Liu, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214411/
https://www.ncbi.nlm.nih.gov/pubmed/30464393
http://dx.doi.org/10.2147/DDDT.S180343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214411/
https://www.ncbi.nlm.nih.gov/pubmed/30464393
http://dx.doi.org/10.2147/DDDT.S180343

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