Tumor-immune profiling of murine syngeneic tumor models as a framework to guide mechanistic studies and predict therapy response in distinct tumor microenvironments

Mouse syngeneic tumor models are widely used tools to demonstrate activity of novel anti-cancer immunotherapies. Despite their widespread use, a comprehensive view of their tumor-immune compositions and their relevance to human tumors has only begun to emerge. We propose each model possesses a uniqu...

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Detalles Bibliográficos
Autores principales: Yu, Jong W., Bhattacharya, Sabyasachi, Yanamandra, Niranjan, Kilian, David, Shi, Hong, Yadavilli, Sapna, Katlinskaya, Yuliya, Kaczynski, Heather, Conner, Michael, Benson, William, Hahn, Ashleigh, Seestaller-Wehr, Laura, Bi, Meixia, Vitali, Nicholas J., Tsvetkov, Lyuben, Halsey, Wendy, Hughes, Ashley, Traini, Christopher, Zhou, Hui, Jing, Junping, Lee, Tae, Figueroa, David J., Brett, Sara, Hopson, Christopher B., Smothers, James F., Hoos, Axel, Srinivasan, Roopa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214511/
https://www.ncbi.nlm.nih.gov/pubmed/30388137
http://dx.doi.org/10.1371/journal.pone.0206223

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