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Peptide T7-modified polypeptide with disulfide bonds for targeted delivery of plasmid DNA for gene therapy of prostate cancer

BACKGROUND: Vectors are essential for successful gene delivery. In the present study, a tumor-targeting cationic gene vector, known as the disulfide cross-linked arginine-aspartic acid peptide modified by HAIYPRH (T7) peptide (CRD-PEG-T7), was designed for targeted delivery of plasmid DNA (pDNA) for...

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Detalles Bibliográficos
Autores principales:	Lu, Yue, Jiang, Wenjun, Wu, Xin, Huang, Saixu, Huang, Zhiyong, Shi, Yamin, Dai, Qi, Chen, Jianming, Ren, Fuzheng, Gao, Shen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214593/ https://www.ncbi.nlm.nih.gov/pubmed/30464450 http://dx.doi.org/10.2147/IJN.S180957

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