CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature

Neuroinflammatory diseases, such as multiple sclerosis, are characterized by invasion of the brain with autoreactive T cells. The mechanism of how T cells acquire their encephalitogenic phenotype and trigger disease remains, however, unclear. The existence of lymphatic vessels in the meninges indica...

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Detalles Bibliográficos
Autores principales: Louveau, Antoine, Herz, Jasmin, Alme, Maria Nordheim, Salvador, Andrea Francesca, Dong, Michael Q., Viar, Kenneth E., Herod, Grace, Knopp, James, Setliff, Joshua, Lupi, Alexander L., Mesquita, Sandro Da, Frost, Elizabeth L, Gaultier, Alban, Harris, Tajie H., Cao, Rui, Hu, Song, Lukens, John R., Smirnov, Igor, Overall, Christopher C., Oliver, Guillermo, Kipnis, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214619/
https://www.ncbi.nlm.nih.gov/pubmed/30224810
http://dx.doi.org/10.1038/s41593-018-0227-9

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