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Optogenetic dissection of mitotic spindle positioning in vivo

The position of the mitotic spindle determines the plane of cell cleavage, and thereby daughter cell location, size, and content. Spindle positioning is driven by dynein-mediated pulling forces exerted on astral microtubules, which requires an evolutionarily conserved complex of Gα∙GDP, GPR-1/2(Pins...

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Detalles Bibliográficos
Autores principales:	Fielmich, Lars-Eric, Schmidt, Ruben, Dickinson, Daniel J, Goldstein, Bob, Akhmanova, Anna, van den Heuvel, Sander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214656/ https://www.ncbi.nlm.nih.gov/pubmed/30109984 http://dx.doi.org/10.7554/eLife.38198

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