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Cathepsin K inhibition preserves compressive load in lumbar vertebrae of osteoporotic monkeys
Anti-resorptive drugs treat bone loss by blocking osteoclast activity through a variety of mechanisms of action. Once significant bone loss has occurred, the ability to restore biomechanical function may differ based on the drug chosen. To assess this question, bisphosphonate (alendronate, ALN) and...
Autores principales: | Colón-Bernal, Isabel D., Duong, Le T., Pennypacker, Brenda, Henderson, James, Kozloff, Kenneth M., Banaszak Holl, Mark M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214835/ https://www.ncbi.nlm.nih.gov/pubmed/30406161 http://dx.doi.org/10.1016/j.bonr.2018.10.001 |
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