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Cathepsin K inhibition preserves compressive load in lumbar vertebrae of osteoporotic monkeys

Anti-resorptive drugs treat bone loss by blocking osteoclast activity through a variety of mechanisms of action. Once significant bone loss has occurred, the ability to restore biomechanical function may differ based on the drug chosen. To assess this question, bisphosphonate (alendronate, ALN) and...

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Detalles Bibliográficos
Autores principales: Colón-Bernal, Isabel D., Duong, Le T., Pennypacker, Brenda, Henderson, James, Kozloff, Kenneth M., Banaszak Holl, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214835/
https://www.ncbi.nlm.nih.gov/pubmed/30406161
http://dx.doi.org/10.1016/j.bonr.2018.10.001

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