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Downregulation of ASPP2 promotes gallbladder cancer metastasis and macrophage recruitment via aPKC-ι/GLI1 pathway

Gallbladder cancer (GBC) is a highly malignant bile duct cancer with poor prognosis due to early invasion and metastasis. However, the molecular mechanisms through which GBC cells interact with the tumor microenvironment (TME) remain poorly understood. Here, we examined the role of the tumor suppres...

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Detalles Bibliográficos
Autores principales: Tian, Li, Deng, Zhengdong, Xu, Lei, Yang, Tao, Yao, Wei, Ji, Lei, Lu, Yun, Zhang, Jian, Liu, Yan, Wang, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214900/
https://www.ncbi.nlm.nih.gov/pubmed/30389910
http://dx.doi.org/10.1038/s41419-018-1145-1