Cargando…
Downregulation of ASPP2 promotes gallbladder cancer metastasis and macrophage recruitment via aPKC-ι/GLI1 pathway
Gallbladder cancer (GBC) is a highly malignant bile duct cancer with poor prognosis due to early invasion and metastasis. However, the molecular mechanisms through which GBC cells interact with the tumor microenvironment (TME) remain poorly understood. Here, we examined the role of the tumor suppres...
Autores principales: | Tian, Li, Deng, Zhengdong, Xu, Lei, Yang, Tao, Yao, Wei, Ji, Lei, Lu, Yun, Zhang, Jian, Liu, Yan, Wang, Jianming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214900/ https://www.ncbi.nlm.nih.gov/pubmed/30389910 http://dx.doi.org/10.1038/s41419-018-1145-1 |
Ejemplares similares
-
aPKCι promotes gallbladder cancer tumorigenesis and gemcitabine resistance by competing with Nrf2 for binding to Keap1
por: Tian, Li, et al.
Publicado: (2019) -
Macrophages-aPKC(ɩ)-CCL5 Feedback Loop Modulates the Progression and Chemoresistance in Cholangiocarcinoma
por: Yang, Tao, et al.
Publicado: (2022) -
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma
por: Ma, Chaoqun, et al.
Publicado: (2020) -
The aPKCι blocking agent ATM negatively regulates EMT and invasion of hepatocellular carcinoma
por: Ma, C Q, et al.
Publicado: (2014) -
Lack of an association between the aPKCλ/ι expression in prostate cancer and the patient outcomes
por: Yokomizo, Yumiko, et al.
Publicado: (2017)