Cargando…

Phosphatidylserine is a marker for axonal debris engulfment but its exposure can be decoupled from degeneration

Apoptotic cells expose Phosphatidylserine (PS), that serves as an “eat me” signal for engulfing cells. Previous studies have shown that PS also marks degenerating axonsduring developmental pruning or in response to insults (Wallerian degeneration), but the pathways that control PS exposure on degene...

Descripción completa

Detalles Bibliográficos
Autores principales: Shacham-Silverberg, Vered, Sar Shalom, Hadas, Goldner, Ron, Golan-Vaishenker, Yarden, Gurwicz, Neta, Gokhman, Irena, Yaron, Avraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214901/
https://www.ncbi.nlm.nih.gov/pubmed/30389906
http://dx.doi.org/10.1038/s41419-018-1155-z