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Phosphatidylserine is a marker for axonal debris engulfment but its exposure can be decoupled from degeneration
Apoptotic cells expose Phosphatidylserine (PS), that serves as an “eat me” signal for engulfing cells. Previous studies have shown that PS also marks degenerating axonsduring developmental pruning or in response to insults (Wallerian degeneration), but the pathways that control PS exposure on degene...
Autores principales: | Shacham-Silverberg, Vered, Sar Shalom, Hadas, Goldner, Ron, Golan-Vaishenker, Yarden, Gurwicz, Neta, Gokhman, Irena, Yaron, Avraham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214901/ https://www.ncbi.nlm.nih.gov/pubmed/30389906 http://dx.doi.org/10.1038/s41419-018-1155-z |
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