Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease

Impaired alveolar formation and maintenance are features of many pulmonary diseases that are associated with significant morbidity and mortality. In a forward genetic screen for modulators of mouse lung development, we identified the non-muscle myosin II heavy chain gene, Myh10. Myh10 mutant pups ex...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Taek, Yin, Wenguang, Jin, Young-June, Panza, Paolo, Gunawan, Felix, Grohmann, Beate, Buettner, Carmen, Sokol, Anna M., Preussner, Jens, Guenther, Stefan, Kostin, Sawa, Ruppert, Clemens, Bhagwat, Aditya M., Ma, Xuefei, Graumann, Johannes, Looso, Mario, Guenther, Andreas, Adelstein, Robert S., Offermanns, Stefan, Stainier, Didier Y. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214918/
https://www.ncbi.nlm.nih.gov/pubmed/30389913
http://dx.doi.org/10.1038/s41467-018-06833-7

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