Aggregatibacter actinomycetemcomitans Leukotoxin Is Delivered to Host Cells in an LFA-1-Indepdendent Manner When Associated with Outer Membrane Vesicles

The Gram-negative bacterium, Aggregatibacter actinomycetemcomitans, has been associated with localized aggressive periodontitis (LAP). In particular, highly leukotoxic strains of A. actinomycetemcomitans have been more closely associated with this disease, suggesting that LtxA is a key virulence fac...

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Detalles Bibliográficos
Autores principales: Nice, Justin B., Balashova, Nataliya V., Kachlany, Scott C., Koufos, Evan, Krueger, Eric, Lally, Edward T., Brown, Angela C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215133/
https://www.ncbi.nlm.nih.gov/pubmed/30322160
http://dx.doi.org/10.3390/toxins10100414

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