Interactions between Triterpenes and a P-I Type Snake Venom Metalloproteinase: Molecular Simulations and Experiments

Small molecule inhibitors of snake venom metalloproteinases (SVMPs) could provide a means to rapidly halt the progression of local tissue damage following viperid snake envenomations. In this study, we examine the ability of candidate compounds based on a pentacyclic triterpene skeleton to inhibit S...

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Detalles Bibliográficos
Autores principales: Preciado, Lina María, Pereañez, Jaime Andrés, Azhagiya Singam, Ettayapuram Ramaprasad, Comer, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215199/
https://www.ncbi.nlm.nih.gov/pubmed/30274214
http://dx.doi.org/10.3390/toxins10100397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215199/
https://www.ncbi.nlm.nih.gov/pubmed/30274214
http://dx.doi.org/10.3390/toxins10100397

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