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Interactions between Triterpenes and a P-I Type Snake Venom Metalloproteinase: Molecular Simulations and Experiments
Small molecule inhibitors of snake venom metalloproteinases (SVMPs) could provide a means to rapidly halt the progression of local tissue damage following viperid snake envenomations. In this study, we examine the ability of candidate compounds based on a pentacyclic triterpene skeleton to inhibit S...
Autores principales: | Preciado, Lina María, Pereañez, Jaime Andrés, Azhagiya Singam, Ettayapuram Ramaprasad, Comer, Jeffrey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215199/ https://www.ncbi.nlm.nih.gov/pubmed/30274214 http://dx.doi.org/10.3390/toxins10100397 |
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