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Remote Microwave and Field-Effect Sensing Techniques for Monitoring Hydrogel Sensor Response

This paper presents two novel techniques for monitoring the response of smart hydrogels composed of synthetic organic materials that can be engineered to respond (swell or shrink, change conductivity and optical properties) to specific chemicals, biomolecules or external stimuli. The first technique...

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Detalles Bibliográficos
Autores principales: Fawole, Olutosin Charles, Dolai, Subhashish, Leu, Hsuan-Yu, Magda, Jules, Tabib-Azar, Massood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215261/
https://www.ncbi.nlm.nih.gov/pubmed/30424459
http://dx.doi.org/10.3390/mi9100526
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author Fawole, Olutosin Charles
Dolai, Subhashish
Leu, Hsuan-Yu
Magda, Jules
Tabib-Azar, Massood
author_facet Fawole, Olutosin Charles
Dolai, Subhashish
Leu, Hsuan-Yu
Magda, Jules
Tabib-Azar, Massood
author_sort Fawole, Olutosin Charles
collection PubMed
description This paper presents two novel techniques for monitoring the response of smart hydrogels composed of synthetic organic materials that can be engineered to respond (swell or shrink, change conductivity and optical properties) to specific chemicals, biomolecules or external stimuli. The first technique uses microwaves both in contact and remote monitoring of the hydrogel as it responds to chemicals. This method is of great interest because it can be used to non-invasively monitor the response of subcutaneously implanted hydrogels to blood chemicals such as oxygen and glucose. The second technique uses a metal-oxide-hydrogel field-effect transistor (MOHFET) and its associated current-voltage characteristics to monitor the hydrogel’s response to different chemicals. MOHFET can be easily integrated with on-board telemetry electronics for applications in implantable biosensors or it can be used as a transistor in an oscillator circuit where the oscillation frequency of the circuit depends on the analyte concentration.
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spelling pubmed-62152612018-11-06 Remote Microwave and Field-Effect Sensing Techniques for Monitoring Hydrogel Sensor Response Fawole, Olutosin Charles Dolai, Subhashish Leu, Hsuan-Yu Magda, Jules Tabib-Azar, Massood Micromachines (Basel) Article This paper presents two novel techniques for monitoring the response of smart hydrogels composed of synthetic organic materials that can be engineered to respond (swell or shrink, change conductivity and optical properties) to specific chemicals, biomolecules or external stimuli. The first technique uses microwaves both in contact and remote monitoring of the hydrogel as it responds to chemicals. This method is of great interest because it can be used to non-invasively monitor the response of subcutaneously implanted hydrogels to blood chemicals such as oxygen and glucose. The second technique uses a metal-oxide-hydrogel field-effect transistor (MOHFET) and its associated current-voltage characteristics to monitor the hydrogel’s response to different chemicals. MOHFET can be easily integrated with on-board telemetry electronics for applications in implantable biosensors or it can be used as a transistor in an oscillator circuit where the oscillation frequency of the circuit depends on the analyte concentration. MDPI 2018-10-17 /pmc/articles/PMC6215261/ /pubmed/30424459 http://dx.doi.org/10.3390/mi9100526 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fawole, Olutosin Charles
Dolai, Subhashish
Leu, Hsuan-Yu
Magda, Jules
Tabib-Azar, Massood
Remote Microwave and Field-Effect Sensing Techniques for Monitoring Hydrogel Sensor Response
title Remote Microwave and Field-Effect Sensing Techniques for Monitoring Hydrogel Sensor Response
title_full Remote Microwave and Field-Effect Sensing Techniques for Monitoring Hydrogel Sensor Response
title_fullStr Remote Microwave and Field-Effect Sensing Techniques for Monitoring Hydrogel Sensor Response
title_full_unstemmed Remote Microwave and Field-Effect Sensing Techniques for Monitoring Hydrogel Sensor Response
title_short Remote Microwave and Field-Effect Sensing Techniques for Monitoring Hydrogel Sensor Response
title_sort remote microwave and field-effect sensing techniques for monitoring hydrogel sensor response
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215261/
https://www.ncbi.nlm.nih.gov/pubmed/30424459
http://dx.doi.org/10.3390/mi9100526
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