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Systemic Administration of Polyelectrolyte Microcapsules: Where Do They Accumulate and When? In Vivo and Ex Vivo Study
Multilayer capsules of 4 microns in size made of biodegradable polymers and iron oxide magnetite nanoparticles have been injected intravenously into rats. The time-dependent microcapsule distribution in organs was investigated in vivo by magnetic resonance imaging (MRI) and ex vivo by histological e...
Autores principales: | Navolokin, Nikita A., German, Sergei V., Bucharskaya, Alla B., Godage, Olga S., Zuev, Viktor V., Maslyakova, Galina N., Pyataev, Nikolaiy A., Zamyshliaev, Pavel S., Zharkov, Mikhail N., Terentyuk, Georgy S., Gorin, Dmitry A., Sukhorukov, Gleb B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215302/ https://www.ncbi.nlm.nih.gov/pubmed/30308931 http://dx.doi.org/10.3390/nano8100812 |
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