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Zebrafish knock-ins swim into the mainstream

The zebrafish is an increasingly popular model organism for human genetic disease research. CRISPR/Cas9-based approaches are currently used for multiple gene-editing purposes in zebrafish, but few studies have developed reliable ways to introduce precise mutations. Point mutation knock-in using CRIS...

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Detalles Bibliográficos
Autores principales: Prykhozhij, Sergey V., Berman, Jason N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215421/
https://www.ncbi.nlm.nih.gov/pubmed/30366936
http://dx.doi.org/10.1242/dmm.037515