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17-DMAG regulates p21 expression to induce chondrogenesis in vitro and in vivo

Cartilage degeneration after injury affects a significant percentage of the population, including those that will go on to develop osteoarthritis (OA). Like humans, most mammals, including mice, are incapable of regenerating injured cartilage. Interestingly, it has previously been shown that p21 (Cd...

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Detalles Bibliográficos
Autores principales: Bertram, Karri L., Narendran, Nadia, Tailor, Pankaj, Jablonski, Christina, Leonard, Catherine, Irvine, Edward, Hess, Ricarda, Masson, Anand O., Abubacker, Saleem, Rinker, Kristina, Biernaskie, Jeff, Yates, Robin M., Salo, Paul, Narendran, Aru, Krawetz, Roman J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215425/
https://www.ncbi.nlm.nih.gov/pubmed/30305302
http://dx.doi.org/10.1242/dmm.033662