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17-DMAG regulates p21 expression to induce chondrogenesis in vitro and in vivo
Cartilage degeneration after injury affects a significant percentage of the population, including those that will go on to develop osteoarthritis (OA). Like humans, most mammals, including mice, are incapable of regenerating injured cartilage. Interestingly, it has previously been shown that p21 (Cd...
Autores principales: | Bertram, Karri L., Narendran, Nadia, Tailor, Pankaj, Jablonski, Christina, Leonard, Catherine, Irvine, Edward, Hess, Ricarda, Masson, Anand O., Abubacker, Saleem, Rinker, Kristina, Biernaskie, Jeff, Yates, Robin M., Salo, Paul, Narendran, Aru, Krawetz, Roman J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215425/ https://www.ncbi.nlm.nih.gov/pubmed/30305302 http://dx.doi.org/10.1242/dmm.033662 |
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