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Mice doubly deficient in Six4 and Six5 show ventral body wall defects reproducing human omphalocele

Omphalocele is a human congenital anomaly in ventral body wall closure and may be caused by impaired formation of the primary abdominal wall (PAW) and/or defects in abdominal muscle development. Here, we report that mice doubly deficient in homeobox genes Six4 and Six5 showed the same ventral body w...

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Detalles Bibliográficos
Autores principales: Takahashi, Masanori, Tamura, Masaru, Sato, Shigeru, Kawakami, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215434/
https://www.ncbi.nlm.nih.gov/pubmed/30237319
http://dx.doi.org/10.1242/dmm.034611

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