The Myc/Max/Mxd Network Is a Target of Mutated Flt3 Signaling in Hematopoietic Stem Cells in Flt3-ITD-Induced Myeloproliferative Disease

Acute myeloid leukemia (AML) has poor prognosis due to various mutations, e.g., in the FLT3 gene. Therefore, it is important to identify pathways regulated by the activated Flt3 receptor for the discovery of new therapeutic targets. The Myc network of oncogenes and tumor suppressor genes is involved...

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Detalles Bibliográficos
Autores principales: Basit, Farhan, Andersson, Maria, Hultquist, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215545/
https://www.ncbi.nlm.nih.gov/pubmed/30420889
http://dx.doi.org/10.1155/2018/3286949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215545/
https://www.ncbi.nlm.nih.gov/pubmed/30420889
http://dx.doi.org/10.1155/2018/3286949

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