Cargando…

DNA methylation levels are associated with CRF(1) receptor antagonist treatment outcome in women with post-traumatic stress disorder

BACKGROUND: We have previously evaluated the efficacy of the CRF(1) receptor antagonist GSK561679 in female PTSD patients. While GSK561679 was not superior to placebo overall, it was associated with a significantly stronger symptom reduction in a subset of patients with probable CRF system hyperacti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pape, Julius C., Carrillo-Roa, Tania, Rothbaum, Barbara O., Nemeroff, Charles B., Czamara, Darina, Zannas, Anthony S., Iosifescu, Dan, Mathew, Sanjay J., Neylan, Thomas C., Mayberg, Helen S., Dunlop, Boadie W., Binder, Elisabeth B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215613/ https://www.ncbi.nlm.nih.gov/pubmed/30390684 http://dx.doi.org/10.1186/s13148-018-0569-x

Ejemplares similares

Evaluation of a corticotropin releasing hormone type 1 receptor antagonist in women with posttraumatic stress disorder: study protocol for a randomized controlled trial
por: Dunlop, Boadie W, et al.
Publicado: (2014)

Combined effects of genotype and childhood adversity shape variability of DNA methylation across age
por: Czamara, Darina, et al.
Publicado: (2021)

Neuroimaging-based biomarkers for treatment selection in major depressive disorder
por: Dunlop, Boadie W., et al.
Publicado: (2014)

Neuroimaging Advances for Depression
por: Dunlop, Boadie W., et al.
Publicado: (2017)

Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity
por: Carrillo-Roa, Tania, et al.
Publicado: (2017)

Assessing Treatment-Resistant Posttraumatic Stress Disorder: The Emory Treatment Resistance Interview for PTSD (E-TRIP)
por: Dunlop, Boadie W., et al.
Publicado: (2014)

“DNA Methylation signatures in panic disorder”
por: Iurato, Stella, et al.
Publicado: (2017)

CRF Receptor Antagonist Astressin-B Reverses and Prevents Alopecia in CRF Over-Expressing Mice
por: Wang, Lixin, et al.
Publicado: (2011)

Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial
por: Dunlop, Boadie W, et al.
Publicado: (2012)

Amygdalar MicroRNA-15a Is Essential for Coping with Chronic Stress
por: Volk, Naama, et al.
Publicado: (2016)

Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling
por: Zannas, Anthony S., et al.
Publicado: (2015)

Correction to: Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling
por: Zannas, Anthony S., et al.
Publicado: (2018)

Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation
por: Lopez, Juan Pablo, et al.
Publicado: (2021)

ERICH3: vesicular association and antidepressant treatment response
por: Liu, Duan, et al.
Publicado: (2020)

Treatment-Specific Hippocampal Subfield Volume Changes With Antidepressant Medication or Cognitive-Behavior Therapy in Treatment-Naive Depression
por: Tai, Hua-Hsin, et al.
Publicado: (2021)

Temporal Profiles and Dose-Responsiveness of Side Effects with Escitalopram and Duloxetine in Treatment-Naïve Depressed Adults
por: Polychroniou, Philip E., et al.
Publicado: (2018)

Stable longitudinal associations of family income with children’s hippocampal volume and memory persist after controlling for polygenic scores of educational attainment
por: Raffington, Laurel, et al.
Publicado: (2019)

Beyond the bins: interpreting and discussing pharmacogenomic reports with psychiatric patients
por: Dunlop, Boadie W.
Publicado: (2020)

Differential Effects of the CRF-R1 Antagonist GSK876008 on Fear-Potentiated, Light- and CRF-Enhanced Startle Suggest Preferential Involvement in Sustained versus Phasic Threat Responses
por: Walker, D., et al.
Publicado: (2008)

Crinecerfont, a CRF(1) Receptor Antagonist, Lowers Adrenal Androgens in Adolescents With Congenital Adrenal Hyperplasia
por: Newfield, Ron S, et al.
Publicado: (2023)

The United States index of socioeconomic deprivation for individuals (USiDep)
por: Dunlop, Boadie W., et al.
Publicado: (2022)

16.4 EFFECT OF GENOTYPE AND EARLY ADVERSITY ENVIRONMENT ON DNA METHYLATION
por: Czamara, Darina, et al.
Publicado: (2018)

Yeast Crf1p: An activator in need is an activator indeed
por: Kumar, Sanjay, et al.
Publicado: (2021)

A Virtual Standardized Patient–Based Assessment Tool to Evaluate Psychiatric Residents’ Psychopharmacology Proficiency
por: Rakofsky, Jeffrey J., et al.
Publicado: (2020)

The Role of Corticotropin-Releasing Factor (CRF) and CRF-Related Peptides in the Social Behavior of Rodents
por: Bagosi, Zsolt, et al.
Publicado: (2023)

Nutrition in children with CRF and on dialysis
por: Rees, Lesley, et al.
Publicado: (2007)

TRANSFoRm eCRF
por: Kuchinke, Wolfgang, et al.
Publicado: (2015)

Nutrition in children with CRF and on dialysis
por: Rees, Lesley, et al.
Publicado: (2008)

Pretreatment with a CRF antagonist amplifies feeding inhibition induced by fourth ventricular cocaine- and amphetamine-regulated transcript peptide
por: Smedh, Ulrika, et al.
Publicado: (2019)

Performance of the Adult ADHD Self-Report Scale-v1.1 in Adults with Major Depressive Disorder
por: Dunlop, Boadie W., et al.
Publicado: (2018)

Psychotherapy or medication for depression? Using individual symptom meta-analyses to derive a Symptom-Oriented Therapy (SOrT) metric for a personalised psychiatry
por: Kappelmann, Nils, et al.
Publicado: (2020)

Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms: A Genetic Correlation and 2-Sample Mendelian Randomization Study
por: Kappelmann, Nils, et al.
Publicado: (2020)

Chemical entity extraction using CRF and an ensemble of extractors
por: Khabsa, Madian, et al.
Publicado: (2015)

Transdiagnostic Clinical Global Impression Scoring for Routine Clinical Settings
por: Dunlop, Boadie W., et al.
Publicado: (2017)

CRF-R1 Antagonist Treatment Exacerbates Circadian Corticosterone Secretion under Chronic Stress, but Preserves HPA Feedback Sensitivity
por: Ibarguen-Vargas, Yadira, et al.
Publicado: (2021)

Caring for Patients with CRF: Rewards and Benefits
por: Karkar, Ayman
Publicado: (2011)

Social effects on AVT and CRF systems
por: Backström, Tobias, et al.
Publicado: (2021)

Gag P2/NC and pol genetic diversity, polymorphism, and drug resistance mutations in HIV-1 CRF02_AG- and non-CRF02_AG-infected patients in Yaoundé, Cameroon
por: Teto, Georges, et al.
Publicado: (2017)

Solanum lycopersicum cytokinin response factor (SlCRF) genes: characterization of CRF domain-containing ERF genes in tomato
por: Shi, Xiuling, et al.
Publicado: (2012)

Molecular Modeling of Structures and Interaction of Human Corticotropin-Releasing Factor (CRF) Binding Protein and CRF Type-2 Receptor
por: Slater, Paula G., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_elcqp4oss6v3f51tvd22hsoq42