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A Selective Histamine H(4) Receptor Antagonist, JNJ7777120, Is Protective in a Rat Model of Transient Cerebral Ischemia
Cerebral ischemia is a multifactorial pathology characterized by different events evolving in time. The acute injury, characterized by excitoxicity, is followed by a secondary brain injury that develops from hours to days after ischemia. Extracellular levels of histamine increase in the ischemic are...
Autores principales: | Dettori, Ilaria, Gaviano, Lisa, Melani, Alessia, Lucarini, Laura, Durante, Mariaconcetta, Masini, Emanuela, Pedata, Felicita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215858/ https://www.ncbi.nlm.nih.gov/pubmed/30420807 http://dx.doi.org/10.3389/fphar.2018.01231 |
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