Sensitivity of epidermal growth factor receptor with single or double uncommon mutations to afatinib confirmed by a visual assay

Patients with non‐small cell lung cancer (NSCLC) harboring common mutations of the epidermal growth factor receptor (EGFR) are sensitive to EGFR‐tyrosine kinase inhibitors (TKI). Although forms of EGFR harboring single uncommon mutations such as G719X or L861Q are thought to be less sensitive to EGF...

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Detalles Bibliográficos
Autores principales: Kimura, Shinichi, Tanaka, Kentaro, Harada, Taishi, Liu, Renpeng, Shibahara, Daisuke, Kawano, Yuko, Nakanishi, Yoichi, Okamoto, Isamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215868/
https://www.ncbi.nlm.nih.gov/pubmed/30255614
http://dx.doi.org/10.1111/cas.13787

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