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PHLDA1, another PHLDA family protein that inhibits Akt

The PHLDA family (pleckstrin homology‐like domain family) of genes consists of 3 members: PHLDA1, 2, and 3. Both PHLDA3 and PHLDA2 are phosphatidylinositol (PIP) binding proteins and function as repressors of Akt. They have tumor suppressive functions, mainly through Akt inhibition. Several reports...

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Detalles Bibliográficos
Autores principales:	Chen, Yu, Takikawa, Masahiro, Tsutsumi, Shuichi, Yamaguchi, Yoko, Okabe, Atsushi, Shimada, Mayuna, Kawase, Tatsuya, Sada, Akane, Ezawa, Issei, Takano, Yuhei, Nagata, Kisaburo, Suzuki, Yutaka, Semba, Kentaro, Aburatani, Hiroyuki, Ohki, Rieko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215895/ https://www.ncbi.nlm.nih.gov/pubmed/30207029 http://dx.doi.org/10.1111/cas.13796

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