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Tumor suppressive role for kinases phosphorylating p53 in DNA damage‐induced apoptosis
Tumor suppressor p53 plays an important role in cancer prevention. Under normal conditions, p53 is maintained at a low level. However, in response to various cellular stresses, p53 is stabilized and activated, which, in turn, initiates DNA repair, cell‐cycle arrest, senescence and apoptosis. Post‐tr...
Autores principales: | Yogosawa, Satomi, Yoshida, Kiyotsugu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215896/ https://www.ncbi.nlm.nih.gov/pubmed/30191640 http://dx.doi.org/10.1111/cas.13792 |
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