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Tumor suppressive role for kinases phosphorylating p53 in DNA damage‐induced apoptosis

Tumor suppressor p53 plays an important role in cancer prevention. Under normal conditions, p53 is maintained at a low level. However, in response to various cellular stresses, p53 is stabilized and activated, which, in turn, initiates DNA repair, cell‐cycle arrest, senescence and apoptosis. Post‐tr...

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Detalles Bibliográficos
Autores principales: Yogosawa, Satomi, Yoshida, Kiyotsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215896/
https://www.ncbi.nlm.nih.gov/pubmed/30191640
http://dx.doi.org/10.1111/cas.13792

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