Oncometabolite induced primary cilia loss in pheochromocytoma

Primary cilia are sensory organelles involved in regulation of cellular signaling. Cilia loss is frequently observed in tumors; yet, the responsible mechanisms and consequences for tumorigenesis remain unclear. We demonstrate that cilia structure and function is disrupted in human pheochromocytomas...

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Detalles Bibliográficos
Autores principales: O’Toole, Samuel M, Watson, David S, Novoselova, Tatiana V, Romano, Lisa E L, King, Peter J, Bradshaw, Teisha Y, Thompson, Clare L, Knight, Martin M, Sharp, Tyson V, Barnes, Michael R, Srirangalingam, Umasuthan, Drake, William M, Chapple, J Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215910/
https://www.ncbi.nlm.nih.gov/pubmed/30345732
http://dx.doi.org/10.1530/ERC-18-0134

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