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New KAT6 inhibitors induce senescence and arrest cancer growth
Lysine acetyltransferases (KATs) catalyze lysine acetylation, a reversible protein modification implicated in a wide variety of disease states. Histone acetyltransferases (HATs) comprise a KAT sub-class that acetylate specific lysines in histones, hence playing an important role in the regulation of...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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KeAi Publishing
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215967/ https://www.ncbi.nlm.nih.gov/pubmed/30417138 http://dx.doi.org/10.1016/j.synbio.2018.10.006 |