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Variants in the 3'-untranslated region of CUL3 is associated with risk of esophageal squamous cell carcinoma

Background: Esophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers in China. Recently, a study identified that cullin 3 (CUL3) was significantly mutated and deleted in ESCC. We then hypothesis that germline variants in CUL3 may also associated with the susceptibility of ESCC. Va...

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Detalles Bibliográficos
Autores principales: Hu, Jin-Long, Hu, Xin-Long, Lu, Chuang-Xin, Chen, Xue-Jiao, Fu, Lei, Han, Qian, Cang, Shun-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216002/
https://www.ncbi.nlm.nih.gov/pubmed/30405832
http://dx.doi.org/10.7150/jca.27052