Comparison of in vitro and in vivo oligomeric states of a wild type and mutant trimeric inner membrane multidrug transporter

Many membrane proteins exist and function as oligomers or protein complexes. Routine analytical methods involve extraction and solubilization of the proteins with detergents, which could disturb their actual oligomeric state. AcrB is a trimeric inner membrane multidrug transporter in E. coli. In pre...

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Detalles Bibliográficos
Autores principales: Wang, Zhaoshuai, Lu, Wei, Rajapaksha, Prasangi, Wilkop, Thomas, Cai, Yuguang, Wei, Yinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216019/
https://www.ncbi.nlm.nih.gov/pubmed/30417130
http://dx.doi.org/10.1016/j.bbrep.2018.10.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216019/
https://www.ncbi.nlm.nih.gov/pubmed/30417130
http://dx.doi.org/10.1016/j.bbrep.2018.10.006

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