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Repurposing of an old drug: In vitro and in vivo efficacies of buparvaquone against Echinococcus multilocularis
The metacestode stage of the fox tapeworm Echinococcus multilocularis causes the lethal disease alveolar echinococcosis. Current chemotherapeutic treatment options are based on benzimidazoles (albendazole and mebendazole), which are insufficient and hence alternative drugs are needed. In this study,...
Autores principales: | Rufener, Reto, Dick, Luca, D'Ascoli, Laura, Ritler, Dominic, Hizem, Amani, Wells, Timothy N.C., Hemphill, Andrew, Lundström-Stadelmann, Britta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216040/ https://www.ncbi.nlm.nih.gov/pubmed/30396011 http://dx.doi.org/10.1016/j.ijpddr.2018.10.011 |
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