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Repurposing of an old drug: In vitro and in vivo efficacies of buparvaquone against Echinococcus multilocularis

The metacestode stage of the fox tapeworm Echinococcus multilocularis causes the lethal disease alveolar echinococcosis. Current chemotherapeutic treatment options are based on benzimidazoles (albendazole and mebendazole), which are insufficient and hence alternative drugs are needed. In this study,...

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Detalles Bibliográficos
Autores principales: Rufener, Reto, Dick, Luca, D'Ascoli, Laura, Ritler, Dominic, Hizem, Amani, Wells, Timothy N.C., Hemphill, Andrew, Lundström-Stadelmann, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216040/
https://www.ncbi.nlm.nih.gov/pubmed/30396011
http://dx.doi.org/10.1016/j.ijpddr.2018.10.011

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