DELTA(2) guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

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Randomised controlled trials are considered to be the best method to assess comparative clinical efficacy and effectiveness, and can be a key source of data for estimating cost effectiveness. Central to the design of a randomised controlled trial is an a priori sample size calculation, which ensures...

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Detalles Bibliográficos
Autores principales: Cook, Jonathan A, Julious, Steven A, Sones, William, Hampson, Lisa V, Hewitt, Catherine, Berlin, Jesse A, Ashby, Deborah, Emsley, Richard, Fergusson, Dean A, Walters, Stephen J, Wilson, Edward C F, MacLennan, Graeme, Stallard, Nigel, Rothwell, Joanne C, Bland, Martin, Brown, Louise, Ramsay, Craig R, Cook, Andrew, Armstrong, David, Altman, Doug, Vale, Luke D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2018
Materias:
Research Methods & Reporting
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216070/
https://www.ncbi.nlm.nih.gov/pubmed/30560792
http://dx.doi.org/10.1136/bmj.k3750
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