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Metastatic melanoma: An unusual cause of gastrointestinal bleeding and intussusception—A case report

INTRODUCTION: Malignant melanoma is responsible for 1–3% of all malignancies being the gastrointestinal tract one of the most common metastatic locations. PRESENTATION OF CASE: We present the case of a 71-year old male with previous history of cutaneous melanoma. Seven years later, while being studi...

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Autores principales: Silva, Sílvia, Tenreiro, Nádia, Melo, Ana, Lage, José, Moreira, Herculano, Próspero, Fernando, Avelar, Paulo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216089/
https://www.ncbi.nlm.nih.gov/pubmed/30396125
http://dx.doi.org/10.1016/j.ijscr.2018.10.057
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author Silva, Sílvia
Tenreiro, Nádia
Melo, Ana
Lage, José
Moreira, Herculano
Próspero, Fernando
Avelar, Paulo
author_facet Silva, Sílvia
Tenreiro, Nádia
Melo, Ana
Lage, José
Moreira, Herculano
Próspero, Fernando
Avelar, Paulo
author_sort Silva, Sílvia
collection PubMed
description INTRODUCTION: Malignant melanoma is responsible for 1–3% of all malignancies being the gastrointestinal tract one of the most common metastatic locations. PRESENTATION OF CASE: We present the case of a 71-year old male with previous history of cutaneous melanoma. Seven years later, while being studied due to suspected small bowel bleeding, he developed small bowel obstruction after being submitted to double balloon enteroscopy. Further investigation revealed small bowel intussusception. He was taken up for emergency laparotomy that confirmed ileal intussusception secondary to an intraluminal mass. We performed segmental enterectomy with primary anastomosis. Histology confirmed intestinal melanoma metastasis. DISCUSSION: Malignant melanoma frequently spreads to the gastrointestinal tract. The presentation is mainly asymptomatic and the diagnosis is often made only after complications develop. Small bowel intussusception and gastrointestinal bleeding are unusual presentations of metastatic melanoma, with few cases reported. Surgical resection not only provides symptom control but also positively affects prognosis. CONCLUSION: Although usually asymptomatic, melanoma metastasis should always be considered in a patient with intestinal symptoms or chronic anemia and personal history of melanoma. Surgical resection is the treatment of choice, leading to an increase in overall survival.
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spelling pubmed-62160892018-11-29 Metastatic melanoma: An unusual cause of gastrointestinal bleeding and intussusception—A case report Silva, Sílvia Tenreiro, Nádia Melo, Ana Lage, José Moreira, Herculano Próspero, Fernando Avelar, Paulo Int J Surg Case Rep Article INTRODUCTION: Malignant melanoma is responsible for 1–3% of all malignancies being the gastrointestinal tract one of the most common metastatic locations. PRESENTATION OF CASE: We present the case of a 71-year old male with previous history of cutaneous melanoma. Seven years later, while being studied due to suspected small bowel bleeding, he developed small bowel obstruction after being submitted to double balloon enteroscopy. Further investigation revealed small bowel intussusception. He was taken up for emergency laparotomy that confirmed ileal intussusception secondary to an intraluminal mass. We performed segmental enterectomy with primary anastomosis. Histology confirmed intestinal melanoma metastasis. DISCUSSION: Malignant melanoma frequently spreads to the gastrointestinal tract. The presentation is mainly asymptomatic and the diagnosis is often made only after complications develop. Small bowel intussusception and gastrointestinal bleeding are unusual presentations of metastatic melanoma, with few cases reported. Surgical resection not only provides symptom control but also positively affects prognosis. CONCLUSION: Although usually asymptomatic, melanoma metastasis should always be considered in a patient with intestinal symptoms or chronic anemia and personal history of melanoma. Surgical resection is the treatment of choice, leading to an increase in overall survival. Elsevier 2018-10-29 /pmc/articles/PMC6216089/ /pubmed/30396125 http://dx.doi.org/10.1016/j.ijscr.2018.10.057 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Silva, Sílvia
Tenreiro, Nádia
Melo, Ana
Lage, José
Moreira, Herculano
Próspero, Fernando
Avelar, Paulo
Metastatic melanoma: An unusual cause of gastrointestinal bleeding and intussusception—A case report
title Metastatic melanoma: An unusual cause of gastrointestinal bleeding and intussusception—A case report
title_full Metastatic melanoma: An unusual cause of gastrointestinal bleeding and intussusception—A case report
title_fullStr Metastatic melanoma: An unusual cause of gastrointestinal bleeding and intussusception—A case report
title_full_unstemmed Metastatic melanoma: An unusual cause of gastrointestinal bleeding and intussusception—A case report
title_short Metastatic melanoma: An unusual cause of gastrointestinal bleeding and intussusception—A case report
title_sort metastatic melanoma: an unusual cause of gastrointestinal bleeding and intussusception—a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216089/
https://www.ncbi.nlm.nih.gov/pubmed/30396125
http://dx.doi.org/10.1016/j.ijscr.2018.10.057
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