PIN1 is a new therapeutic target of craniosynostosis

Gain-of-function mutations in fibroblast growth factor receptors (FGFRs) cause congenital skeletal anomalies, including craniosynostosis (CS), which is characterized by the premature closure of craniofacial sutures. Apert syndrome (AS) is one of the severest forms of CS, and the only treatment is su...

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Detalles Bibliográficos
Autores principales: Shin, H R, Bae, H S, Kim, B S, Yoon, H I, Cho, Y D, Kim, W J, Choi, K Y, Lee, Y S, Woo, K M, Baek, J H, Ryoo, H M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216213/
https://www.ncbi.nlm.nih.gov/pubmed/30007339
http://dx.doi.org/10.1093/hmg/ddy252

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