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Methadone Dosage and Plasma Levels, SNPs of OPRM1 Gene and Age of First Drug Use Were Associated With Outcomes of Methadone Maintenance Treatment

Objective: To explore the association between methadone dosage, plasma drug concentration, SNPs of μ-opioid receptor gene (OPRM1), ATP-binding cassette subfamily B member 1 gene (ABCB1), and methadone maintenance treatment (MMT) response. Method: A total of 240 Chinese Han participants receiving MMT...

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Detalles Bibliográficos
Autores principales:	Peng, Sufang, Jiang, Haifeng, Du, Jiang, Lin, Shuxing, Pan, Shujun, Yu, Shunying, Zhao, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216325/ https://www.ncbi.nlm.nih.gov/pubmed/30420869 http://dx.doi.org/10.3389/fgene.2018.00450

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