Arminin 1a-C, a novel antimicrobial peptide from ancient metazoan Hydra, shows potent antileukemia activity against drug-sensitive and drug-resistant leukemia cells

PURPOSE: Due to the emergence of multidrug resistance (MDR), traditional antileukemia drugs no longer meet the treatment needs. Therefore, new antileukemia drugs with different action mechanisms are urgently needed to cope with this situation. MATERIALS AND METHODS: Arminin 1a-C is an antimicrobial...

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Detalles Bibliográficos
Autores principales: Liang, Xiaolei, Wang, Ruirui, Dou, Wenshan, Zhao, Li, Zhou, Lanxia, Zhu, Junfang, Wang, Kairong, Yan, Jiexi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217004/
https://www.ncbi.nlm.nih.gov/pubmed/30464401
http://dx.doi.org/10.2147/DDDT.S181188

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